Press releases
New study analyzes early antibody binding to decellularized homografts
Semi-quantitative analysis by a newly developed Dot-Blot showed early binding of preformed antibody binding in 20 consecutive patients, which were followed after pulmonary and aortic valve replacement with cell-free homografts....
European Journal for Cardiothoracic Surgery publishes ESPOIR 5-year data
A 5-year analysis of ESPOIR Trial patients was performed to provide an insight into the midterm performance of decellularized pulmonary homografts (DPH). ESPOIR Trial and Registry patients were matched with cryopreserved...
5-year ESPOIR Trial results and ESPOIR Registry Data to be presented at the DGTHG/DGPK 2022
The 5-year results of the prospective European multi-centre ESPOIR trial will be presented as an on-demand presentation within the 2022 DGTHG/DGPK meeting in Hamburg. The talk will also focus on the available longterm data from...
Newly developed method helps to quantify the residual immunogenic potential of decellularized human heart valves
Dot-blot techniques demonstrate highly individual immune response towards decellularized homografts - Results published Open Access in the European Journal of Cardio-Thoracic-Surgery
Presentation of the early ARISE results at the 2019 Meeting of the European Association for Cardio-Thoracic-Surgery (EACTS) Saturday 5th of October in Lisbon, Portugal
Results for pediatric aortic valve replacement using cell-free homografts will be presented as well at the EACTS 2019 [more]
Early results of the ESPOIR Trial published in 2019
The publication of the early ESPOIR Trial and the midterm ESPOIR Registry results has been cited more than 20 times since 2019 and lists upon the most cited publications within the European Journal of Cardio-Thoracic-Surgery... [more]
Patient lecture and seminar on regenerative heart valves and stem cell therapy options - 30.03.2019 in the Hannover Zoo
Patientenseminar: Regenerative Therapien und Stammzelltherapie bei angeborenen Herzfehlern – geht das schon? [more]
EACTS 2018 in Milano - Initial results from the prospective ESPOIR Trial and ESPOIR Registry data presented on Thursday 18th of October 2018
Early data from the ESPOIR Trial was presented at the EACTS Annual Meeting in Milano on 18th of October in a Rapid Response Session. The abstract of the presentation can be found here on the site 6. [more]
“For me, it’s a day at work, for the child it’s the rest of their life”
Great Ormond Street Hospital (GOSH) is situated in the heart of London and is the world's oldest children hospital (est. 1852) with the patronage of Queen Elisabeth herself. Today the hospital is considered an international... [more]
Final project report - Summary
Beginning in January 2012, the European Union has funded the European Clinical Study for the Application of Regenerative Heart Valves, coordinated by Hannover Medical School, Germany, with a grant of 5.2 Million Euros over a... [more]
ESPOIR project closing meeting held in Zurich in December 2016
Long-term follow up initiated - the European post-authorisation study on regenerative pulmonary heart valve replacement enrolled 120 patients [more]
Publication about the first ten years of clinical experience with decellularized homografts for pulmonary valve replacement / Patient inclusion to the ESPOIR clinical trial
Surgeons, cardiologists and pediatric cardiologists from Hannover Medical School/Germany and the University Hospital in Chisinau/Moldavia have published the clinical experience derived from ten years of clinical experience using... [more]
Patient inclusion on the increase for the ESPOIR clinical study
The ESPOIR study group, comprising 7 hospitals from Hannover, Chisinau, London, Leuven, Leiden, Padua, Zurich and 4 homograft banks from Brussels, Hannover, Treviso and Rotterdam, has now reached full operative capacity. This has... [more]
A decade of clinical experience with decellularized homografts presented at the 2015 EACTS
Researchers from Hannover Medical School, Germany and Universitatea Nicolae Testemitianu, Chisinau, Moldavia presented their clinical experience with fresh, non-cryopreserved, decellularized pulmonary homografts over the last ten... [more]
First ESPOIR decellularized homografts implanted at “KiSpi” and “GOSH”
Two of the largest paediatric hospitals in Europe, Kinderspital Zürich (UZH) and Great Ormond Street Hospital (GOSH) in London, have successfully implanted decellularized homografts for pulmonary valve replacement within the... [more]