Press releases

21 April 2015

First ESPOIR decellularized homografts implanted at “KiSpi” and “GOSH”

Two of the largest paediatric hospitals in Europe, Kinderspital Zürich (UZH) and Great Ormond Street Hospital (GOSH) in London, have successfully implanted decellularized homografts for pulmonary valve replacement within the... [more]

11 March 2015

Holding up under pressure: the MHH heads clinical study on lifelong aortic heart valve replacements EU awards 5 million Euro to the ARISE project

March 2015 saw the Kick-off Meeting of the EU-funded clinical study "Aortic Valve Replacement using Individualised Regenerative allografts: Bridging the Therapeutic Gap", which is to receive 5 million Euro in funding... [more]

30 January 2015

ESPOIR study start at KU Leuven / New EU-project ARISE

Belgian surgeons, led by Prof. Bart Meyns, successfully implanted the first ESPOIR PV valve within the ESPOIR study at the University hospital of the Katholieke Universiteit Leuven on the 22th of January 2015. KU Leuven... [more]

16 September 2014

Successful start for the ESPOIR study at Moldova State Medical University

A team of Moldavian surgeons, led by Prof. Anatol Ciubotaru, successfully operated the first patient in Chisinau/Mo on Wednesday, 03 September 2014. In an uneventful procedure, the young female patient received a decellularized... [more]

25 August 2014

ESPOIR clinical study start offers new hope for patients with congenital heart disease

A leading European consortium, headed by Hannover Medical School (MHH), has launched the ESPOIR clinical study on regenerative heart valves, with the first two enrolled patients undergoing valve replacement surgery at the MHH in... [more]

02 May 2014

No significant early activation of the cellular immune response after implantation of decellularized fresh pulmonary homografts

The longevity of homografts for heart valve replacement is determined by the amount of activation of the recipients' immune system caused by antigen reaction against the donated heart valve. Fresh decellularized pulmonary... [more]

02 May 2014

ESPOIR receives ENCePP Study Seal / ClinicalTrials.gov Identifier NCT02035540

The European Clinical Study for the Application of Regenerative Heart Valves received the ENCePP seal and has been officially registered in the ENCePP E-Register of Studies as a Post Authorization Safety Study (PASS), Ref. Number... [more]

09 October 2013

Third ESPOIR Steering Committee Meeting at the 2013 EACTS in Vienna / German authorities approved Espoir PV

The ESPOIR Steering Committee (SC) convened for the third time during the 27th EACTS Annual Meeting in Vienna. The German competent authority Paul-Ehrlich-Institut approved the study valve -ESPOIR PV-  a decellularized... [more]

12 November 2012

Steering Committee Meeting

The ESPOIR Steering Committee Meeting took place on 30th of October 2012 in Barcelona at the 26th EACTS Annual Meeting. During the Scientific Programme Prof. Haverich gave an update on the “Clinical results with in vitro unseeded... [more]

01 August 2012

Leuven new clinical partner within the ESPOIR study

Leuven with Prof. Dr. Bart Meyns, Head of Cardiac Surgery - Cardiale Heelkunde, University Hospitals, Katholieke Universiteit Leuven has been officially added by the European Commission to the ESPOIR project partners. Prof.... [more]

12 May 2012

Ten years of innovative heart valves from Hannover

Bright eyes and happy smiles on the faces of children, young people and adults alike are nothing unusual at Hannover Adventure Zoo. On Saturday, however, it was a very special group that met at the zoo to have fun together:... [more]

09 March 2012

„Medical history being made in Hannover“

The medicine of tomorrow is already reality today: on a visit to Hannover Medical School (MHH), Federal Minister Dr Ursula von der Leyen, the patron of the association promoting children’s heart centres in Germany... [more]

02 January 2012

Transplantation: study on heart valves that last a lifetime

Transplanting a heart valve that is not rejected, lasts a lifetime and, in children, even grows with the body – this is the aim of the ‘European clinical study for the application of regenerative heart valves’ (ESPOIR). Headed by... [more]

22 November 2011

TV report: Will artificial and pig heart valves soon be a thing of the past?

Professor Haverich gives TV interview for the medical magazine programme ‘Visite’ On 22 November 2011 at 8.15 p.m. in its feature item entitled ‘New heart valves: which method for which patient?’ the NDR network’s health show... [more]

13 May 2011

Minister Wanka opens new cleanroom facility

Minister Johanna Wanka puts the cleanrooms into operation at the touch of a button.Hannover has taken another leap forward in the field of biotechnology: on 16 May, Hannover Medical School (MHH) opened its new cleanrooms: special... [more]

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