Press releases

16 March 2023

Decellularized pulmonary homografts exhibit better results than bovine jugular vein conduits

A recent publication in the journal of Cell and Tissue Banking analyzed the results of a matched comparison of decellularized pulmonary homografts (DPH) and bovine jugular vein (BJV) conduits for pulmonary valve replacement in...

20 October 2022

New study analyzes early antibody binding to decellularized homografts

Semi-quantitative analysis by a newly developed Dot-Blot showed early binding of preformed antibody binding in 20 consecutive patients, which were followed after pulmonary and aortic valve replacement with cell-free homografts....

27 April 2022

European Journal for Cardiothoracic Surgery publishes ESPOIR 5-year data

A 5-year analysis of ESPOIR Trial patients was performed to provide an insight into the midterm performance of decellularized pulmonary homografts (DPH). ESPOIR Trial and Registry patients were matched with cryopreserved...

28 January 2022

5-year ESPOIR Trial results and ESPOIR Registry Data to be presented at the DGTHG/DGPK 2022

The 5-year results of the prospective European multi-centre ESPOIR trial will be presented as an on-demand presentation within the 2022 DGTHG/DGPK meeting in Hamburg. The talk will also focus on the available longterm data from...

22 February 2021

Newly developed method helps to quantify the residual immunogenic potential of decellularized human heart valves

Dot-blot techniques demonstrate highly individual immune response towards decellularized homografts - Results published Open Access in the European Journal of Cardio-Thoracic-Surgery

22 July 2019

Presentation of the early ARISE results at the 2019 Meeting of the European Association for Cardio-Thoracic-Surgery (EACTS) Saturday 5th of October in Lisbon, Portugal

Results for pediatric aortic valve replacement using cell-free homografts will be presented as well at the EACTS 2019 [more]

18 March 2019

Early results of the ESPOIR Trial published in 2019

The publication of the early ESPOIR Trial and the midterm ESPOIR Registry results has been cited more than 20 times since 2019 and lists upon the most cited publications within the European Journal of Cardio-Thoracic-Surgery... [more]

15 February 2019

Patient lecture and seminar on regenerative heart valves and stem cell therapy options - 30.03.2019 in the Hannover Zoo

Patientenseminar: Regenerative Therapien und Stammzelltherapie bei angeborenen Herzfehlern – geht das schon? [more]

01 October 2018

EACTS 2018 in Milano - Initial results from the prospective ESPOIR Trial and ESPOIR Registry data presented on Thursday 18th of October 2018

Early data from the ESPOIR Trial was presented at the EACTS Annual Meeting in Milano on 18th of October in a Rapid Response Session. The abstract of the presentation can be found here on the site 6.  [more]

09 March 2018

“For me, it’s a day at work, for the child it’s the rest of their life”

Great Ormond Street Hospital (GOSH) is situated in the heart of London and is the world's oldest children hospital (est. 1852) with the patronage of Queen Elisabeth herself. Today the hospital is considered an international... [more]

09 June 2017

Final project report - Summary

Beginning in January 2012, the European Union has funded the European Clinical Study for the Application of Regenerative Heart Valves, coordinated by Hannover Medical School, Germany, with a grant of 5.2 Million Euros over a... [more]

20 December 2016

ESPOIR project closing meeting held in Zurich in December 2016

Long-term follow up initiated - the European post-authorisation study on regenerative pulmonary heart valve replacement enrolled 120 patients [more]

01 March 2016

Publication about the first ten years of clinical experience with decellularized homografts for pulmonary valve replacement / Patient inclusion to the ESPOIR clinical trial

Surgeons, cardiologists and pediatric cardiologists from Hannover Medical School/Germany and the University Hospital in Chisinau/Moldavia have published the clinical experience derived from ten years of clinical experience using... [more]

27 October 2015

Patient inclusion on the increase for the ESPOIR clinical study

The ESPOIR study group, comprising 7 hospitals from Hannover, Chisinau, London, Leuven, Leiden, Padua, Zurich and 4 homograft banks from Brussels, Hannover, Treviso and Rotterdam, has now reached full operative capacity. This has... [more]

27 October 2015

A decade of clinical experience with decellularized homografts presented at the 2015 EACTS

Researchers from Hannover Medical School, Germany and Universitatea Nicolae Testemitianu, Chisinau, Moldavia presented their clinical experience with fresh, non-cryopreserved, decellularized pulmonary homografts over the last ten... [more]

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